Particle Line Assembly/Patterning by Microfluidic AC Electroosmosis

Microfluidic Transport by AC Electroosmosis

AC Electro-osmosis (ACEO) is a newly developed microfluidic mechanism, which can transport fluids and particles with low voltage that is suitable for integration with IC circuitry. We observed line formation of particles on electrodes by ACEO, leading to better understanding of ACEO microflows. Also by identifying a new ACEO mechanism from electrochemical reaction, we developed Asymmetric Polar...

Microfluidic manipulation by AC Electrothermal effect

Improved Protein Binding Rate for Bio- Sensors Using Ac Electroosmosis

Many biosensors are limited by long detection times that result from transport limitations of large macromolecules such as proteins which must reach the active surface in order to be detected. To overcome this difficulty, a common biosensor, the quartz crystal microbalance was modified with a microelectrode pattern capable of producing AC electroosmosis. The mixing pattern that is thereby gener...

AC Electroosmosis-Enhanced Nanoplasmofluidic Detection of Ultralow-Concentration Cytokine.

Label-free, nanoparticle-based plasmonic optical biosensing, combined with device miniaturization and microarray integration, has emerged as a promising approach for rapid, multiplexed biomolecular analysis. However, limited sensitivity prevents the wide use of such integrated label-free nanoplasmonic biosensors in clinical and life science applications where low-abundance biomolecule detection...

Model based design of a microfluidic mixer driven by induced charge electroosmosis.

Mixing chemical or biological samples with reagents for chemical analysis is one of the most time consuming operations on microfluidic platforms. This is primarily due to the low rate of diffusive transport in liquid systems. Additionally, much research has focused on detection, rather than sample preparation. In response, we describe a mixer for microfluidic sample preparation based on the ele...